Science

How smoking sets the stage for lung cancer, glimpsed in new study

Chronic smoke exposure alters lung stem cells and weakens their safety mechanisms and local immune defences, creating a precancerous state; common KRAS and TP53 mutations triggered tumours only in smoke-conditioned tissue, showing how smoking primes cells for cancer

· 11/2/2026, 5:20:11 PM· 2 min read
How smoking sets the stage for lung cancer, glimpsed in new study
Chronic smoke exposure alters lung stem cells and weakens their safety mechanisms and local immune defences, creating a precancerous state; common KRAS and TP53 mutations triggered tumours only in smoke-conditioned tissue, showing how smoking primes cells for cancer
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